New ‘molecular switch’ allows control of gene therapy doses: Scientists

New York: Paving the way for solving a major safety issue associated with gene therapies, scientists have developed a special molecular switch that could be embedded into such therapies to allow doctors to control dosing.

The feat offers gene therapy designers what may be the first viable technique for adjusting the activity levels of their therapeutic genes.

The lack of such a basic safety feature has helped limit the development of gene therapy, which otherwise holds promise for addressing genetically based conditions.

“I think that our approach offers the only practical way at present to regulate the dose of gene therapy in an animal or a human,” said lead researcher Michael Farzan from the Scripps Research Institute in Jupiter in Florida, US. (IANS)

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